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Zafgen makes progress in development of obesity drug beloranib
TweetMethionine aminopeptidase 2. Source: PDBbot. http://bit.ly/IP0hBW On November 15, 2013 obesity specialty company Zafgen (Cambridge, MA) announced the results of its Phase 2 study of beloranib in...
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Will Novartis lead a pharma industry return to neuroscience R&D?
TweetPyramidal neurons. Source: Retama. http://bit.ly/18j9iOP A prominent feature of pharmaceutical company strategy in recent years has been massive cuts in R&D. These cutbacks have hit...
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Neuroscience companies sprout up in Boston
TweetPyramidal neurons. Source: Magnus Manske http://bit.ly/1gUo6GM In our December 10, 2013 blog article that focused on Novartis’ new neuroscience division, we briefly mentioned two young Cambridge...
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Breakthrough of the year 2013–Cancer Immunotherapy
TweetHappy New Year! Source: Roblespepe. http://bit.ly/1cpkyHX As it does every year, Science published its “Breakthrough of the Year” for 2013 in the 20 December 2013 issue of the ...
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Can Merck’s R&D restructuring enable it to improve its productivity?
TweetSimvastatin (Merck’s Zocor) On December 27th, 2013 the Wall Street Journal published an article by staff reporters Peter Loftus and Jonathan Rockoff about Merck’s new R&D restructuring....
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RNAi therapeutics stage a comeback
TweetTransthyretin protein structure Not so long ago, the once-promising field of RNA interference (RNAi)-based drugs was on the downswing. This was documented in our August 22, 2011 article on ...
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Thalidomide, multiple myeloma, Protein-Protein interactions, and drug discovery
TweetIkaros. Source © Marie-Lan Nguyen / Wikimedia Commons Thalidomide is a notorious drug that was approved in Europe in the late 1950s for use as a sedative, but was ...
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Neandertals, diabetes, and drug discovery
TweetIn our 2010 end-of-year blog article entitled “2010: Breakthroughs, Newsmakers, And Deals Of The Year”, we proposed an alternative nominee for the life science breakthrough of the year: ...
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Forma Therapeutics’ expanded R&D collaboration with Celgene
Tweet? Ubiquitin pathway. Source: Rogerdodd, English language Wikipedia On April 1, 2014, Forma Therapeutics (Watertown MA) announced that it had entered into an expanded strategic collaboration with...
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Agios Pharmaceuticals continues to progress
TweetAgios Kirykos, Ikaria, Greece. Source: http://commons.wikimedia.org/wiki/File:Agios_Kirikos,_Ikaria.jpg Because of being very busy with other projects, we have not posted an article on this blog...
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Cancer Immunotherapy Report Published By CHI Insight Pharma Reports
TweetT cells attached to tumor cell. Source: MSKCC. http://bit.ly/1uPr5nl ? On September 9, 2014, Cambridge Healthtech Institute’s (CHI’s) Insight Pharma Reports announced the publication of a new...
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Obesity therapeutics update
TweetObesity, 12th century Japan. The Biopharmconsortium Blog has over the years included numerous articles about obesity, and the attempts of researchers and companies to develop treatments for this...
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Late-breaking cancer immunotherapy news
Tweet Source: Medical Progress Today 12/14/12http://bit.ly/1sPO1WU In our September 16, 2014 article on this blog, we announced the publication by Cambridge Healthtech Institute’s (CHI’s) Insight...
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Vertex cystic fibrosis therapeutics update
Tweet? CFTR protein: A. normal B. gating mutant.Source: Lbudd14 http://bit.ly/1rGrzJ1 As we said in our September 10, 2014 article, we intended to post updates on companies that (Read more...)
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The Genentech/NewLink alliance, the IDO/TDO pathway, and targeting metabolism...
TweetIndoleamine 2,3-dioxygenase 1 On October 20, 2014, New Link Genetics Corporation (Ames, IA) announced that it had entered into an exclusive worldwide license agreement with Genentech/Roche for...
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